High level briefing
Tadagra is an oral product that contains the active molecule tadalafil. It is most often promoted for men who experience erectile dysfunction (ED) and is sometimes used for lower urinary tract symptoms linked to benign prostatic enlargement. The information below is tailored to people in the United Kingdom.
- Tadalafil is the key active ingredient
- Typical condition(s) treated: Erectile dysfunction; may relieve some symptoms of benign prostatic hyperplasia
- Strength referenced on this page: each tablet holds 20 mg (information on lower daily strengths also included)
Navigation shortcuts: How the system operates, How to take stock, Alternative options and rates, Legal and purchasing guidance.
Purpose and mode of operation
Tadalafil belongs to the class of medicines known as phosphodiesterase type 5 inhibitors. When sexual stimulation occurs, tadalafil helps preserve cyclic GMP levels in penile tissue, which improves blood inflow and supports erection maintenance. For men with bladder outlet symptoms due to an enlarged prostate, tadalafil can relax smooth muscle in the prostate and bladder neck, which may ease urinary difficulties.
If you have conditions that might make tadalafil unsafe for you, consult Cases where treatment is not appropriate and Protective guidelines before use.
Dosing notes and directions
Always follow dose administration directions from a prescriber or pharmacist. Tablets should be swallowed whole with water unless directed otherwise.
- For intermittent use (as-needed) with a 20 mg tablet: take one tablet roughly 30 minutes before sexual activity; do not take more than one dose in any 24 hour period.
- Daily dosing: some people are prescribed a low daily dose (for example 2.5 mg or 5 mg) for continuous effect or for treatment of urinary symptoms; the 20 mg tablet is not normally prescribed for daily use.
- Timing: if you are on a once-daily regimen, try to take the dose at the same time each day to maintain steady levels.
Avoid grapefruit juice while taking tadalafil because it can raise blood concentrations. Drinks that contain alcohol can reduce erectile ability and may increase minor side effects such as dizziness or lightheadedness.
Precautionary steps
Discuss the following topics with your clinician prior to starting Tadagra:
- Any history of heart disease, chest pain on exertion, heart failure, or symptoms during sex such as breathlessness or angina.
- Anatomical problems of the penis (for example Peyronie disease) or conditions that raise the risk of prolonged erection.
- Past sudden loss of vision or hearing, or inherited retinal disorders such as retinitis pigmentosa.
- There is dysfunction of the kidney or liver.
- Low blood pressure or uncontrolled hypertension.
Seek urgent medical care if an erection lasts longer than four hours (risk of priapism) or if you develop sudden visual or auditory loss.
Tadagra is a medicine intended for adults. It is not recommended for use in children or for routine use in women.
Use is contraindicated in these cases
- Known allergy to tadalafil or any ingredient contained in the tablet.
- Concurrent use of nitrates or nicorandil, including recreational alkyl nitrites ("poppers"), because combined use can cause a dangerous fall in blood pressure.
- Use with riociguat (a pulmonary hypertension medicine) is not allowed.
- Recent major cardiovascular events: for example, myocardial infarction within the last 90 days or stroke within the last 6 months, or unstable cardiac conditions.
- Severe liver injury or significant hypotension, and certain cardiac structural or rhythm disorders as judged by your clinician.
- Heritable retinal diseases such as retinitis pigmentosa.
If you are unsure whether tadalafil is suitableappraisal your medical history with the prescriber and consult Partnered effective the give and take of interactions require clear communication. between medicines for medicines that can affect safety.
Potential reactions to therapy
Many harmful bodily effects are mild and resolve without treatment:
- Painful head
- Gastric distress or dyspeptic distress
- Back and/or muscle pain
- Seasonal nasal congestion
- Giddiness
Stop taking the medicine and seek medical attention for chest pain, fainting, sudden hearing or vision changes, signs of a severe allergic reaction, or a painful erection that lasts more than four hours.
Drug communication in action considerations
Provide a full list of current medicines, supplements and herbal products to your healthcare professional. Some combinations can produce harmful effects.
- Drugs containing nitrates or nicorandil: absolute contraindication due to severe hypotension risk.
- Riociguat: should not be taken together with tadalafil.
- Alpha-blockers used for blood pressure or prostate symptoms: may cause additive blood pressure lowering and require careful monitoring.
- Strong inhibitors or inducers of the CYP3A4 enzyme (for example some antiretrovirals, azole antifungals, certain macrolide antibiotics, and some anticonvulsants): these can change tadalafil levels and may necessitate dose adjustments.
- Discuss other medicines such as diabetes treatments, respiratory therapies, opioid or non-steroidal pain medicines, and psychoactive drugs in alliance with your prescriber.
Cross-check When this should not be used and Safety guidelines for related important safety notes.
Missed dose event
- As-needed regimen: if you forget a planned as-needed dose, take it when you remember provided you do not exceed one dose in 24 hours.
- Daily regimen: take the missed tablet as soon as you remember unless it is near the time for your next dose; do not double up to catch up.
Drug having an overdose
If you suspect an a drug overdose case or notice severe symptoms after taking tadalafil, contact emergency services (999) or NHS 111 immediately, or attend the nearest emergency department. Bring the medication packaging with you if possible.
Storage
- Keep tablets in a cool, dry place away from direct heat and humidity.
- Protect medicine from direct sunlight and store out of reach of children and pets.
- Do not use after the expiry date shown on the carton. Return unused medicines to a pharmacy for safe disposal.
Alternative options for cost analysis for price comparison (UK approximate)
Several more treatment options can be considered depending on personal preference, side effect profile, onset and duration of action, and cost. Below are typical private prices per tablet in Great Britain Pounds (GBP). These are approximate retail figures and will vary by supplier, pack size, and whether a branded or generic product is chosen.
- Generic tadalafil (10 mg to 20 mg as-needed; 2.5 mg to 5 mg daily): roughly 1 to 3 GBP per tablet depending on strength and pack size.
- Branded Cialis (tadalafil): around 5 to 10 GBP per tablet for higher strengths; daily 5 mg tablets may cost 2 to 6 GBP each in multipacks.
- Avanafil brand Spedra: commonly 3 to 6 GBP per tablet.
- Vardenafil (Levitra or generics): typically 2 to 5 GBP per tablet.
- Sildenafil generics (commonly 50 to 100 mg): about 0.20 to 1.00 GBP per tablet; branded Viagra is often 5 to 8 GBP per tablet.
Non-pill options include vacuum erection devices, intracavernosal injections (for example alprostadil), and specialist counseling for psychological causes. These variant options have different costs, unintended effects and suitability; discuss options with a prescriber.
For more on a system differences and suitability, see A guide to using it and how the process functions.
UK statutory status and purchasing guidance
- Tadalafil is a prescription-only medicine (POM) in the United Kingdom; a valid NHS or private prescription is required to buy it legally.
- Only sildenafil 50 mg (Viagra Connect) is available without a prescription under pharmacy supervision; tadalafil is not available over the counter in the UK.
- The Medicines and Healthcare products Regulatory Agency (MHRA) regulates medicines. Community pharmacies and internet pharmacies must be registered with the General Pharmaceutical Council (GPhC). Reputable UK online suppliers will display their GPhC registration details.
- Importing prescription medicines for personal use without a UK prescription may result in seizure by Border Force. Products manufactured outside the UK may not comply with UK quality standards; unlicensed brands should be treated with caution.
- Products labelled as Tadagra or other foreign generics may not be authorized in the UK. Always verify supplier credentials and that an appropriate clinical assessment is carried out before supply.
Before ordering onlinecheck this, please. the seller's GPhC registration and that they require a proper medical assessment. For non-urgent advice call NHS 111; for emergencies call 999.
Additional information
If you experience dizziness or feel faint after taking tadalafil, do not drive or operate machinery until the symptoms resolve. Review Absolute conditions that contraindicate treatment for conditions that may make tadalafil unsafe for you.
This page is an informational summary and does not replace individual medical advice. Ask for counsel a qualified healthcare professional for personalized recommendations.
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