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Ivermectin is the chief active ingredient.
Common brand: Stromectol. Generic ivermectin tablets may also be supplied in the UK when prescribed by an authorised clinician.
Therapeutic group: antiparasitic medicine. It is not intended as an antibiotic. Everyday signs include strongyloidiasis and onchocerciasis; clinicians may also prescribe it for scabies and certain lice infestations when appropriate.
Typical tablet strengths available by prescription: 3 mg, 6 mg and 12 mg. Dosing is determined by the prescriber based on the condition being treated, the patient weight and current clinical mentoring and guidance. Some regimens are single doses, while other situations require repeated dosing or combined topical therapy.
Before you take charge this medicine
Give your prescriber a full list of your current medicines and your medical history. Tell them if any of the following apply to you:
- Preexisting liver disease or recently abnormal liver blood tests.
- Known allergy to ivermectin or to any excipients in the tablet
- Pregnant, trying to conceive or breastfeeding
- History of convulsive episodes, other significant neurological problems, or frequent fainting
- Severe respiratory disease such as asthma that is not well controlled
- Residence in, or recent travel to, regions where Loa loa (African eye worm) is endemic
The youth population: oral ivermectin is used with caution in small children. Many prescribers avoid routine use in children below certain weight thresholds unless advised by a specialist. Always seek a clinician's advice for pediatric dosing.
What is the recommended dose and method for taking this medicine?
- Swallow tablets whole with a full glass of water.
- Take on an empty stomach where instructed: commonly at least 30 minutes before eating or at least 2 hours after a meal.
- If you have more than one dose, try to take it at the same time of day for consistency.
- Do not increase the dose or frequency beyond what your prescriber has ordered. Finish the prescribed plan even if symptoms improve.
- Avoid grapefruit and grapefruit juice during treatment as these can change blood levels of some medicines.
Pediatric advice: consult a paediatric clinician for dose calculations and special considerations.
Suspected suspected overdose: contact NHS 111, your local emergency department or a poison control service immediately.
If you miss a dose
When you forget a dose, take it as soon as you remember, unless the next dose is due soon. If it is almost time for the next dose, skip the missed tablet and continue your usual dosing schedule. Do not take two tablets at once to substitute for a i missed the medication dose.
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Certain medicines and substances can alter how ivermectin acts or increase the chance of accompanying effects. Tell your clinician about all prescription medicines, over-the-counter drugs, herbal remedies and supplements you use.
- Strong inhibitors of CYP3A4 or P-glycoprotein such as ketoconazole, ritonavir, cobicistat, clarithromycin and some calcium channel blockers
- Warfarin and other anticoagulants are used to manage thrombosis risk., which may require closer INR supervision and monitoring
- Other medicines that cause drowsiness or sedation, and alcohol, which can worsen dizziness
- Products containing grapefruit or grapefruit juice
This list is not exhaustive. Always verify the data. with your prescriber or pharmacist about specific combinations.
Hygiene monitoring of operational health and sanitation during treatment
Your clinician may ask you to return for follow-up visits or tests to ensure the infection has cleared. Follow-up might include stool tests, skin checks or eye assessments depending on the parasite being treated.
Measures to reduce the chance of reinfection or spread:
- Wash hands regularly and keep nails short and clean
- Change bed linen and underwear frequently while being treated and launder at high temperatures where practical
- Maintain regular personal hygiene and clean commonly touched surfaces and bathrooms
Contact your prescriber if symptoms persist, get worse or if you develop signs of a severe reaction such as high fever, marked swelling of glands or eye symptoms after treatment.
Foreseeable undesired reactions to monitor
Reach out for urgent medical help for serious reactions, which are uncommon but require prompt attention:
- Signs of an allergic reaction: widespread rash, hives, swelling of the face, throat or tongue, difficulty breathing
- Chest pain or a heart rate that is rapid and inconsistent.
- Seizure episodes, profound confusion or fainting
- Severe eye symptoms: pain, redness, swelling or sudden change in vision
- High fever or painful, extensive swelling
- Severe blistering, peeling skin or sores (including inside the mouth)
- New loss of bladder or bowel control
More commonly reported, usually milder effects include:
- Cranial ache
- Nausea and vomiting complaints with abdominal discomfort.
- Diarrhoeal illness or constipation
- Difficulty eating due to reduced appetite
- Joint and muscle pains and tremor
- Tender lymph nodes in the neck, armpit or groin
If you notice persistent or worrying collateral effects, contact your healthcare provider for advice.
Navigate back to continuous monitoring in real time and hygiene
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- Keep medicines out of sight and out of reach of children.
- Store at room temperature below 30 degrees C (86 degrees F) in a tightly closed container away from direct heat and moisture.
- Do not use after the date of expiry listed on the packaging.
- Return unused or out-of-date medicines to a pharmacy for proper disposal; do not discard into household waste or drains.
Different courses of action and medicines related to them
Depending on the infection and also the patient, UK clinicians may recommend a contingency option or adjunct therapies:
- Permethrin 5 percent cream for scabies; 1 percent topical or other formulations are used for head lice
- Topical treatments such as dimeticone or spinosad for head lice
- Benzyl benzoate or malathion lotions where appropriate
- Oral agents such as albendazole or mebendazole for certain intestinal helminths
- Diethylcarbamazine (DEC) for some filarial infections under specialist supervision
- Note: Veterinary ivermectin products are not licensed for human use and must not be used as a substitute for prescribed human medicines
Choice of therapy depends on the parasite species, patient age, weight, pregnancy status, local resistance patterns and clinical sound advice. Oral ivermectin is often reserved for specific scenarios, for example crusted scabies or when topical treatment has failed, and is used under clinician direction.
Typical UK price windows (private purchase estimates)
Prices vary by pharmacy, brand, pack size and whether the medicine is supplied privately or via the NHS. The ranges below are indicative for private purchase as of current routine market levels in the UK.
- Ivermectin tablets (3 mg to 12 mg): roughly 10 GBP to 40 GBP for small prescription packs commonly used in single-dose or short-course regimens; larger or repeated courses may be more expensive
- Permethrin 5 percent cream (30 g to 60 g): about 5 GBP to 15 GBP
- Malathion lotion: around 10 GBP to 20 GBP
- Dimeticone or spinosad lice treatments: typically 5 GBP to 15 GBP
- Albendazole or mebendazole oral preparations: roughly 10 GBP to 60 GBP depending on formulation and quantity
On the NHS, prescription costs are subject to current NHS charging rules and may be lower for eligible patients. Always check for issues. live prices with a UK-registered pharmacy before purchase.
UK information on law and accessible justice
- Prescription status: oral ivermectin is designated as a Prescription Only Medicine (POM) in the UK. A valid prescription from a clinician registered in the UK is required to obtain it legally for human use.
- Where to obtain: use pharmacies registered with the General Pharmaceutical Council. Legitimate UK online pharmacies will display the appropriate distance selling logo and details.
- Importing medicines: import rules are strict. Small quantities for personal use may sometimes be permitted but this is subject to current MHRA rules. Unauthorised imports can be seized or return to the initial stateed. It is wise to check before proceeding. official MHRA guidance prior to ordering medicines from outside the UK.
- Advertising and claims: it is unlawful in the UK to advertise prescription-only medicines directly to the public. Be cautious of websites or advertisements making unverified or sensational claims about treatments.
- Off-label use: do not self-prescribe or use ivermectin for conditions not advised by an authorised clinician. Follow the prescriber or specialist's directions at all times.
- Driving and machinery: if you experience dizziness, drowsiness or visual disturbances while taking ivermectin, do not drive or operate machinery until you are confident it is safe to do so.
- Safe disposal: return unused or expired medicines to a pharmacy for safe disposal rather than disposing in household waste or via drains.
For authoritative and current information consult NHS.uk, the Medicines and Healthcare products Regulatory Agency (MHRA) along with the General Pharmaceutical Council (GPhC).
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