Overview and scope
Gabapentin, commonly sold under brand names such as Neurontin, is an anticonvulsant medicine used in the United Kingdom for certain types of epilepsy and for neuropathic pain, including pain after shingles (post-herpetic neuralgia). For practical guidance on taking the medicine see the dosing information section at Step by step guide to using. For legal and prescribing rules see Facts about UK law.
Typical strengths available in the UK include 100 mg, 300 mg, 400 mg, 600 mg and 800 mg formulations in capsule or tablet forms. Dosage and formulation will be chosen by your prescriber based on the condition treated and individual factors.
Main takeaways
- Gabapentin is the active ingredient.
- Drug group: anticonvulsant; commonly repurposed for neuropathic pain.
- Take the medicine by mouth with water, keeping to consistent times each day.
- Do not stop gabapentin abruptly without medical advice; sudden withdrawal can trigger seizures or other undesirable effects.
- In the UK gabapentin is a prescription-only medication and is also a controlled drug (see legal details).
Ahead of starting treatment
Tell your clinician about any health issues and medicines you use so the risks and benefits can be assessed. Important items to mention include:
- Chronic kidney disease or if you are receiving dialysis.
- A past or present history of depression, suicidal thoughts, self-harm, or other serious mental health problems in you or close relatives.
- Any allergy to gabapentin or other ingredients in the product, or reactions to medicines, food dyes or preservatives.
- If you are expecting, planning to conceive, or breastfeeding.
- Breathing problems or regular use of opioids, sedatives, benzodiazepines, or heavy alcohol use.
If you are caring for someone who will take gabapentin, ensure you pass this information on to the prescribing clinician.
Guidelines for using this medicine
Follow the exact dosing instructions with cautions provided on your prescription label or by your prescriber. Gabapentin is swallowed with water and may be taken with food if it upsets the stomach. Aim to space doses evenly across the day as directed.
- If tablets are prescribed to be split, follow any instructions on how to store and use halves; unused halves should be managed according to label instructions or pharmacy advice.
- Pupils may need specialist dosing. Do not give adult doses to children without specialist expert counsel.
- If you suspect an he overdosed, contact NHS 111, your local emergency department or a poison control service right away.
For details on other medicines and substances that may alter the effect of gabapentin see Human the pattern of collaborative interactions determines group dynamics..
Should you skip a dose
Should you forget a dose, take it promptly when you remember, unless the next dose is within four hours. In that case skip the i forgot to take a dose and continue with your usual schedule. Do not take two doses as a replacement for a i forgot to take a dose.
Potentially arising personal engagement and communications build trust and rapport.
Several medicines and preparations can alter gabapentin absorption or increase sedation and breathing risk. Common interpersonal engagements with others are the core of collaboration. you should monitor include:
- Antacids containing aluminum or magnesium: may reduce gabapentin absorption if taken together. Leave at least two hours between doses.
- Opioid analgesics such as morphine: combined use can increase drowsiness coupled with the risk of respiratory depression.
- Phosphate binders like sevelamer: may lower gabapentin levels due to reduced absorption.
- Some non-steroidal anti-inflammatory drugs: may alter gabapentin pharmacokinetics slightly.
- Alcohol content by volume, benzodiazepines, sleeping tablets and other sedatives: increase the risk of dizziness, drowsiness and breathing problems.
This list is not comprehensive. Always give your clinician a complete list of prescription drugs, over-the-counter remedies, supplements and recreational substances you use.
Warning alerts and performance monitoring while using gabapentin
- Do not stop taking gabapentin suddenly without medical advice; your prescriber will usually reduce the dose gradually if treatment is to be ended.
- Keep a simple diary of symptoms and seizure frequency if relevant, and share this at follow-up appointments.
- Consider carrying a card or wearing an identity bracelet that lists your condition and current medicines.
- Unsteadiness, drowsiness or blurred vision can occur. Avoid driving or using machinery until you know how gabapentin affects you. Peruse the annotations for legal use on driving in Information concerning UK law.
- To reduce lightheadedness, get up slowly from chairs or beds. Avoid drinking alcohol while taking gabapentin because effects can be amplified.
- If you notice mood changes, increasing depression or thoughts of harming yourself, seek urgent medical help.
Recognizing knock-on effects and when to seek assistance
Turn to medical services immediately for severe symptoms. serious reactions such as:
- Signs of an allergic reaction: widespread rash, hives, swelling of the face, lips, mouth or throat, trouble breathing.
- New or worsening depression, suicidal thoughts, or sudden changes in behaviour.
- Severe drowsiness or breathing difficulties, especially if gabapentin is used with opioids or other sedatives.
More common in general, usually mild.er latent effects that may improve over time include:
- Spinning sensation, sleepiness or problems with coordination.
- Nausea, constipation or other gastrointestinal upset.
- Tremor, slurred speech or unsteady walking.
- Weight change and dry mouth.
If mild effects persist or are troublesome, discuss dose changes or alternate care options together with your clinician.
Global storage capacity determines how much you can keep. and disposal practice
- Ensure medicines are placed where children cannot locate or reach them.
- Store at normal room temperatures, typically between 15 and 30 degrees C.
- Do not dispose of gabapentin by flushing it down the toilet or putting it in household waste. Visit a pharmacy to return medicines you no longer need or that are expired for safe disposal.
Alternative medicines and analogous drugs
Treatment choices depend on the condition being treated, patient characteristics and previous response to medicines. Some spare options commonly considered in the UK include:
- Pregabalin (for example Lyrica): similar action to gabapentin; tends to allow faster dose escalation but may cause dizziness in some patients.
- Amitriptyline: a tricyclic antidepressant often used for chronic nerve pain; sedative effects can be helpful at night.
- Duloxetine treatment: an SNRI antidepressant useful in some forms of neuropathic pain.
- Carbamazepine: used for trigeminal neuralgia and certain seizure types; has significant mutual interaction potential.
- Other antiepileptics such as lamotrigine, valproate and topiramate: choice depends on seizure type, age, pregnancy plans and comorbidities.
Discuss the relative benefits, likely residual effects and intercommunication profiles of these options with your prescriber involved. For cost information, consult the pricing details. Costs in the United Kingdom.
Prices and cost considerations in the UK
How much you pay depends on whether you use NHS prescriptions or obtain medication privately:
- NHS prescriptions: in England most items attract a standard charge per item (around 9.90 pounds as of 2024). Residents of Scotland, Wales and Northern Ireland pay no prescription charges. Concessions and prepayment certificates can reduce or remove charges.
- Private pharmacy prices vary by brand, strength and pack size. Typical approximate ranges for a 28 to 30 day supply are:
- Gabapentin (generic): roughly 5 to 20 pounds depending on dose and pack size.
- Pregabalin (generic or branded Lyrica): often 6 to 25 pounds for common regimens.
- Amitriptyline (generic): commonly inexpensive, around 1 to 5 pounds for low dose packs used in pain management.
These are approximate retail figures and exclude any consultation fees. Prices can differ between high street pharmacies, online pharmacies and branded versus generic products. Always confirm current prices at the point of sale.
United Kingdom information pertaining to the law
- Status under law: gabapentin is a prescription-only medicine and is classified as a controlled drug in the UK (controlled as Schedule 3 under the Misuse of Drugs Regulations).
- Prescriptions: Schedule 3 rules require that the total quantity prescribed is written in words and figures. Repeat dispensing is generally not permitted for Schedule 3 controlled drugs and emergency supplies are limited.
- Dispensing and storage capacity determines how much you can keep.: pharmacists may ask for identification. Gabapentin is not subject to safe custody cabinets like some other controlled drugs, but it remains subject to specific recording requirements.
- Travel: when travelling abroad with gabapentin take medicines in original packaging and bring a copy of the prescription or a letter from your prescriber. Some countries require special authorisation for controlled medicines; check the destination country rules in advance.
- Driving and work: do not drive or operate heavy machinery if you feel drowsy or impaired. Driving while impaired by medication can be an offence.
- Sharing or supplying: do not share prescribed medicines. Possession without a prescription may be unlawful and could have legal consequences.
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